Are you fascinated by the complexity of living cells’ interior? Do you enjoy playing with models of proteins and other biomolecules in the computer? Would you like to use the tools of physics, chemistry, and mathematics to describe processes in cells?
We are a recently founded research group focusing on the multi-scale computer simulation of the cell interior. In particular, we look into how the local structure and dynamics of the intracellular environment can control metabolic processes. Our research is supported by the prestigious Lumina Quaeruntur Award as well as by a grant from the Czech Science Foundation.
Our group is based at J. Heyrovský Institute of Physical Chemistry in Prague, Czech Republic. The group is integrated into the young and interdisciplinary Department of Computational Chemistry, connecting the physical chemistry and biophysics of proteins and membranes with theoretical enzymology and spectroscopy.
Interested in joining our team? Don’t hesitate to contact us for more information.
Postdoctoral Position in the Molecular Modeling of Processes in Enzyme Assemblies
The postdoctoral associate will contribute to the implementation and deployment of a multi-scale framework to couple molecular simulations of enzymes and ligands in dynamic enzyme assemblies with kinetic models of metabolic pathways. This framework will allow us to explore mechanisms underlying spatial organization and control of metabolic pathways in cells.
The initial contract period is for one year with the possibility of extending up to three years.
Requirements:
- PhD in Physics, Physical Chemistry, Computational Biology, or a related field
- Proficiency in scientific programming (e.g., Python, C, C++)
- Strong skills in developing and implementing mathematical models of molecular processes
- Experience with coarse-grained and all-atom classical MD simulations
- Excellent communication and collaboration skills
Experience with protein modeling, computational software development, and developing software interfaces to integrate different simulation programs will be considered an asset.
To apply, please send your CV, a list of publications, a motivation letter, and contact information for two references to recruitment@jh-inst.cas.czand stepan.timr@jh-inst.cas.cz. Please include SC2024_36 in the email subject line.
Link to the official announcement at the Heyrovský Institute’s website.