A comprehensive census of 18 distinct types of amino-acid interactions, conducted by Tom Miclot, our team’s founding postdoc, reveals the importance of the often-overlooked support region in protein complex assembly. Check out our paper, just published in Protein Science.
The analysis was made possible by our newly developed software (made available at https://github.com/TMiclot/MICLOT), which has proven to be a powerful tool for identifying diverse interaction types, classifying interacting residue pairs, and characterizing their local interaction contexts within both stable and transient interfaces.
