I am looking for a postdoctoral associate with strong background in computational structural biology and protein modeling to become a member of a newly established research team focusing on the computer simulation of cell interior. Using multi-scale molecular models, we aim to elucidate physical and chemical mechanisms governing the spatial organization of metabolic pathways in living cells. The postdoctoral researcher will model protein structures for use in multi-scale simulations of dynamic enzyme assemblies, predict protein–protein, protein–RNA, and protein–metabolite interactions, and evaluate allosteric effects arising from such interactions.
The initial contract period will be for 1 year with a possible extension to up to 5 years and with the possibility of research stays in collaborating laboratories (France, Germany, USA). The research team is integrated into the young and interdisciplinary Department of Computational Chemistry, connecting the physical chemistry and biophysics of proteins and membranes with theoretical enzymology and spectroscopy.
Starting date: January 2023 (can be negotiated).
The ideal candidate has obtained their PhD in computational biology, bioinformatics, computational chemistry, or a related field with the focus on protein structural modeling and/or protein complex prediction. Experience with molecular dynamics simulations, modeling of intrinsically disordered proteins and RNA, as well as with the prediction of liquid–liquid phase separation would be a strong plus. Excellent communication and collaboration skills are essential.
If you are interested, please send us your CV together with a list of publications, your motivation letter, and two contacts as a reference to firstname.lastname@example.org. Please write in the subject line of your email SC2022_27. For any technical questions, contact email@example.com.
Application deadline: November 9, 2022
Here is the link to the official advertisement by Heyrovský Institute with more details.